Speech biomarkers mapped to the clinical scales your trial already runs.

New recordings on the participant's phone, tablet or computer, or recordings your study already holds, read on the clinical scale the study uses.

Speech is a window into the nervous system

Speaking draws on the brain, the breath, the larynx and the articulators. One short recording carries signal from all of them.

Cognitive
Brain
Memory, word-finding and fluency.
Motor speech
Articulators
Articulation, timing and verbal output.
Voice
Larynx
Phonation, voice quality and prosody.
Breath
Lungs
Respiratory support and phonation time.

How a reading is made

What the scales record at visits, read from speech between them

Voice is inherently multi-modal: a couple of minutes of speech carries cognitive and motor signal at once. We decompose it into interpretable, disease-specific domains.

Mapped to the trial's scale

MMSE · MoCA
Reading on the MMSE and MoCA
MDS-UPDRS
Reading on the MDS-UPDRS speech item
cUHDRS · UHDRS
Mapped to the cUHDRS spoken components
ALSFRS-R
Reading on the ALSFRS-R speech item
Each reading is reported on the clinical scale the study already uses. Where the interview or session is recorded, speech also serves trial QC

A digital measure that scales.

A woman at her kitchen table speaking into her phone
01

Non-invasive

A short recorded task. No imaging, no clinic burden on the participant.

02

No dedicated device

Runs on the participant’s own phone, tablet or computer. Nothing to ship.

03

Cross-language

One architecture across languages.

04

Low burden

Low participant effort supports frequent, remote sampling between site visits.

05

Objective and repeatable

Quantitative features, scored the same way at every visit.

06

Extends reach

Automated analysis extends assessment to settings where frequent in-clinic testing is impractical.

One recording, three streams, one multi-stream model

Input Three streams Output One recording home task onsite assessment clinical interview Deep-learning embeddings learned representations Acoustic-linguistic features voice, timing, articulation Cognitive-linguistic features words, content, structure multi-stream The study’s own scale one per indication Alzheimer's MMSE · MoCA Parkinson's MDS-UPDRS speech Huntington's cUHDRS components ALS ALSFRS-R speech
Existing recordings
Audio a study already holds
Speech extracted from audio or video, with the rater's voice separated from the participant's, linked to the rating from the same visit.
New recordings
A short task, onsite and at home
A reference recording at the visit, then the same task between visits on the participant's phone, tablet or computer.

How the three streams work

Validation following DiMe V3

Following the Digital Medicine Society’s V3 framework.

Verification
Checked at capture
Level, noise, clipping and completeness are checked on every recording, with device and versions logged.
Analytical validation
Processing change
Robustness to on-device processing change, presented at the Digital Biomarkers in Clinical Trials Summit in Basel and at ISCTM, 2026.
Clinical validation
On the trial’s scale
Readings evaluated against the MMSE and MoCA in Alzheimer’s and MCI, against the MDS‑UPDRS speech item in Parkinson’s, and the ALSFRS‑R speech item in ALS. In Huntington’s, speech separated premanifest gene carriers from controls.

Validation

Deploying speech biomarkers in real-world studies

A configurable platform for the design, administration and remote conduct of studies that collect speech. Participants record in the browser, in the app or over a phone call, at home or in clinic.

Discover the platform

Collecting now

Speech is being collected now in Alzheimer's, MCI, BPSD, Parkinson's and Huntington's, on the participant's own devices.

Alzheimer's and MCI

Türkiye · United States

BPSD

Türkiye

Parkinson's disease

United States · Germany

Huntington's disease

United States

Presented in 2026

AD/PD 2026 · ePosters
Fully explainable speech biomarkers
Two ePosters: AD/MCI screening and Parkinson's screening.
Basel · June 2026
Digital Biomarkers in Clinical Trials Summit
When the Device Changes Mid-Trial: Evaluating Speech-Based Digital Endpoint Robustness to On-Device Preprocessing Variability in Longitudinal Remote Monitoring
Philadelphia · September 2026
ISCTM Autumn Conference
When the Device Changes Mid-Trial: Speech-Based Digital Endpoint Robustness to On-Device Preprocessing Variability

All posters & reports

Bring speech biomarkers into your trial.

Tell us about the indication and endpoint you're working toward, and we'll share how our platform fits.

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